A Sulfamethoxazole Electrochemical Sensor Based Upon Polyphenylenediamine/Multiwalled Carbon Nanotubes

A sulfamethoxazole (SMX)-molecularly imprinted polymer (MIP) was fabricated by polyphenylenediamine. The composite prepared by the fabricated SMX-MIP and multi-walled carbon nanotubes (OH-functionalized type) was used for modification of a carbon paste electrode. The cyclic voltammetry technique was employed to follow the electrochemical attitude of SMX on the prepared electrode and to determine the optimized conditions for using the sensor in the SMX analysis. Differential pulse voltammetry technique was used to evaluate the figures of merit, selectivity, and application of the developed electrode in SMX determinations. The latter investigations revealed the linearity attitude of the investigated sensor in the range ۱.۰×۱۰-۶–۹.۰×۱۰-۳ mol/L of SMX (with the LOD ۴.۵×۱۰-۷ mol/L and the RSD of ۳.۴۵%). The validation of the method was checked by independent HPLC analysis of the assessed real samples.

کلیدواژه ها:

Sulfamethoxazole ، Molecularly imprinted polymer ، Polyphenylenediamine ، Multi-Walled Carbon Nanotube ، Electrochemical sensor