Lentinula Edodes Polysaccharides and Wound Healing

Introduction: Wound healing is an essential process for repairing of damaged tissues and the community Healthcaring. Lentinula edodes (shiitake) is a medicinal and edible mushroom cultivated in East Asia for thousands of years. Polysaccharides, natural and biocompatible components, have significant potential in enhancing of wound healing. In this study, polysaccharides of Lentinus edodes extract was evaluated for its effects as a candidate for wound healing. Materials and Methods Hot water extracted polysaccharide from mycellium of L. edodes was purified by DEAE column chromatography. FT-IR spectroscopy, and thin-layer chromatography was investigated to understanding molecular characteristics. Antibmicrobial effect of polysaccharides was confirmed against S. aureus and E. coli. Results The results indicated that polysaccharides can promote faster wound healing by creating antimicrobial and antioxidant activities. FT-IR spectroscopy, and thin-layer chromatography showed that polysaccharide composed of glucose units. Biological activity assays confirmed that L. edodes polysaccharides have both antimicrobial and antioxidant activities. Conclusion Functional characteristics of polysaccharides can make them as suitable candidates in wound treatment and also modern medicines. Polysaccharides can increase wound healing and also decrease the risk of microbial growth. polysaccharides serve as natural and effective agents in wound healing, showing promise for clinical applications. Further research is needed to optimize formulations and explore their clinical uses.

کلیدواژه ها:

Polysaccharides