Exciting Advances in Nanoengineering of Zinc Oxide Nanoparticles - based Composites for Enhanced Wound Healing

The wound healing process is a complex biological process requiring therapeutic interventions to accelerate it. Due to their unique antibacterial and anti-inflammatory properties, zinc oxide nanoparticles have a high potential for promoting better wound healing. Zinc oxide nanoparticles can control the infection of the wound site and, as a result, its effective regeneration when integrated into the composition of biocompatible composites. Nanocomposites based on zinc nanoparticles are a suitable alternative for traditional wound care methods. Zinc oxide nanoparticles have emerged as a valuable solution to the challenges of wound healing due to their reaction with cellular processes and the ability to combat bacterial infections. Incorporating these nanoparticles with biocompatible polymers such as collagen, gelatin, chitosan, and polyethylene glycol improves the physico-mechanical properties of wound dressings and strengthens their bioactive properties. Methods like electrospinning and chemical deposition should be used to prepare Zinc Oxide NP-based composites, providing precise control over the dispersion of nanoparticles. Zinc oxide nanoparticles prevent infection in the wound site by creating reactive oxygen species, accelerating the activity of fibroblasts and keratinocytes, improving wound closure and tissue repair. These structures have shown efficiency in various wound-healing applications by reducing the risk of infection, accelerating the healing process, and enhancing collagen deposition essential for tissue regeneration. Films and hydrogels based on zinc oxide nanoparticles are particularly effective in wound healing due to their sustained antibacterial function and the creation of a favorable healing environment.

کلیدواژه ها:

Zinc Oxide Nanoparticles ، Wound Healing ، Nanoengineering ، Biocompatible Composites ، Antibacterial ، Tissue Regeneration