From Nano to Macro: The Influence of Graphene Oxide Nanostructures on Biological Pathways in Wound Healing

Wound healing, a critical process involving a sequence of biological events, is now being revolutionized by the potential of nanomaterials, particularly graphene oxide (GO). This innovative material, with its exceptional mechanical strength, high surface area, and biocompatibility, offers significant advantages for wound healing applications. Its interaction with key biological pathways can enhance cellular activities like migration, proliferation, and differentiation, thereby accelerating tissue regeneration. This review delves into how GO modulates significant pathways, including the Wnt/β-catenin, TGF-β, MAPK/ERK, and PI۳K/Akt signaling pathways, to improve wound healing outcomes.

کلیدواژه ها:

Graphene Oxide ، Nanostructures ، Biological Pathways ، Wound Healing