Conductive Hydrogels Based on Alginate/Polyaniline for Tissue Engineering Applications

Tissue engineering requires scaffolds that mimic the extracellular matrix to support cell growth and tissue regeneration. Hydrogels, with their high water content and biocompatibility, are commonly used in these scaffolds. Sodium alginate (SA), a biopolymer derived from brown algae, is favored for its non-toxic nature and ability to form stable gels via ionic cross-linking. However, traditional hydrogels lack conductivity, which limits their applications in tissues like nerve, muscle, cardiac and bone tissue, where electrical signals play a crucial role. By incorporating conductive polymers such as polyaniline (PANI), the hydrogels gain electroactive properties, which can stimulate cell proliferation and differentiation, enhancing their potential for general tissue engineering applications.

کلیدواژه ها:

Conductive hydrogels ، Alginate ، Polyaniline ، Tissue engineering ، Biocompatibility ، Electroactivity