Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases

سال انتشار: 1403
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 10

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شناسه ملی سند علمی:

WTRMED11_025

تاریخ نمایه سازی: 14 خرداد 1404

چکیده مقاله:

Exosomes, which are nanoscale vesicles secreted by almost all cell types via paracrine pathways, play a crucial role in intercellular communication. Exosomes are small extracellular nanovesicles that are released by cells, and their potential has been explored for use in cosmetics, skincare, tissue regeneration, and dermatological diseases. Exosomes have been widely exploited for nearly a decade to develop novel biological therapeutic strategies for recalcitrant clinical problems. The therapeutic value of exosomes lies in their ability to modulate the microenvironment of cells, regulate gene expression, and induce cell differentiation, which can positively impact skin health. In terms of cosmetics, exosomes have been used to reduce wrinkles, improve skin texture and hydration, enhance skin elasticity, and reduce inflammation and damage caused by UV radiation. Furthermore, exosomes have been used to promote tissue regeneration in skin wounds and to treat dermatological diseases such as systemic lupus erythematosus, psoriasis, atopic dermatitis, systemic sclerosis, pigment regulation, vitiligo, and hair growth. The existing literature demonstrated that with further research, exosomes may become a viable therapeutic option for many skin conditions.

نویسندگان

Ehsan Taghiabadi

Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran