۲-[۱۸F]-FDG PET/CT in Rasmussen Encephalitis: Guiding Diagnosis and Treatment in a Young Adult with Sudden Onset

Rasmussen encephalitis (RE) is a rare condition characterized by chronic inflammatory disorder due to a unilateral inflammation of the cerebral cortex. Typically, it involves one cerebral hemisphere and manifests through intractable epileptic seizures. Its occurrence in adults is infrequent with late onset RE (lo-RE) being a challenging diagnosis in few cases. We present a case of a ۲۸-year-old woman who was brought to the emergency room due to the sudden onset of uncontrolled seizures. The MRI interpretation was uncertain and the use of ۲-[۱۸F]-FDG PET/CT (FDG-PET) scan helped in the differential diagnosis between autoimmune seronegative or Rassmussen encephalitis.Even though FDG-PET is not a mandatory diagnostic criterion in the clinical evaluation of RE patients, the presented case and the available literature data suggest its usefulness as a valuable diagnostic tool in assessing patients with doubtful diagnosis, emphasizing its potential as a reliable adjunct in challenging diagnostic scenarios and for patient follow-up.

کلیدواژه ها:

Neuroimaging ، cerebral FDG PET ، Autoimmune Encephalitis