Application of rapid expansion of supercritical solution in the synthesis of Paracetamol drug nanoparticles

In this study, the reduction in size of paracetamol particles is investigated using the rapid expansion of supercritical solution (RESS) process. Based on the results, the largest paracetamol particle size was ≤ ۸۰ nm, exhibiting quasi-spherical morphology compared to unprocessed particles, which had a needle shape and a mean particle size of ۱۰۰ μm.

کلیدواژه ها:

RESS ، Supercritical CO۲ ، Paracetamol ، nanoparticle