Smartphone-based colorimetric detection of rutin by copper-guanosine nanorods (Cu-Guo NRs) as a laccase mimicking nanozyme

Colorimetric sensing of rutin (Rtn) based on Cu-guanosine nanorods (NRs) is developed based on the spectrophotometric method in this paper. Observations of significant changes in absorbance peak with a red shift confirm the formation of the oxidized form of Rtn due to the activity of Cu-Guo NRs. The color change from green to dark yellow allows for visual detection of Rtn within a concentration range of ۷۷۰ nM to ۵۴.۴۶ µM by a limit of detection (LOD) of ۱۱۴ nM. This method successfully measured Rtn in various real samples including propolis dry extract and human biofluids, demonstrating its good applicability. The sensor's sensitivity, selectivity, cost-effectiveness and ease of use, promise significant support for routine analysis in real-world applications.

کلیدواژه ها:

Rutin ، Copper-guanosine nanorods ، Nanozyme ، Smartphone