Green synthesis of pyrimidinedione derivatives by employing ZnFe۲O۴/GA nanoparticles as a powerful and recyclable catalyst

An efficient method for the synthesis of chromene pyrimidine-۲,۴-dione derivatives using glutamic acid supported on ZnFe۲O۴ nanoparticles (ZnFe۲O۴/GA) as a heterogeneous catalyst is presented. The reaction involves ۴-hydroxycoumarin, aromatic aldehydes and ۶-aminouracil in H۲O as a green solvent at room temperature. The ZnFe۲O۴/GA shows high catalytic activity, easy separation using an external magnetic field, and reusability for up to four consecutive cycles, offering an eco-friendly and sustainable catalytic system.

کلیدواژه ها:

multicomponent reaction ، pyrimidinone ، magnetic nanoparticles