N-Arylation of Guanidines by CuO Nanoparticles and Ligand-Free

The copper oxide nano-catalysis cross-coupling reactions between aryl halides and guanidines to produce N-aryl guanidines have been developed. Mild reaction conditions, good yields, ligand-free, easy work-up, no column chromatography, and ease of handling at room temperature are the main aspects of the method.

کلیدواژه ها:

N-Arylation ، Ullmann coupling ، Guanidine ، Copper-catalyzed ، Aryl halides