Micro- and nanocarriers for improving therapeutic effects of phenolic compounds: An up-to-date perspective

Phenolic compounds have shown potential antioxidant, anti-inflammatory, antimicrobial, and anticancer activities, which can be optimized by their formulations at micro- and nanoscales. Bioavailability, controlled release, and targeted delivery features of micro- and nanoformulations of phenolic compounds such as flavonoids have enhanced their applications in various therapeutic fields. Micro- and nanoformulations of these compounds have presented new avenues for upgrading their therapeutic effects by reducing conventional therapeutic limitations. Therefore, a promising approach for the next generation of therapeutic applications has been expected by improved bioavailability, targeted delivery, controlled release, and mitigation of side effects. This review will explore recent advancements and clinical limitations in the micro- and nanoformulations of phenolic compounds.

کلیدواژه ها:

Enhanced bioavailability ، Targeted Delivery ، Controlled release ، Minimized side effects