Memorizing Al-Quran Increases Serum BDNF Levels

Cognitive function refers to mental processes involving knowledge, information processing, and reasoning. Memorizing the Al-Quran can stimulate the production of brain-derived neurotrophic factor (BDNF), a crucial protein that plays a significant role in promoting the survival of neurons and synapses involved in memory and learning. BDNF levels can be used to assess cognitive function. Mild Cognitive Impairment (MCI) is often evaluated using the MOCA-INA score. This study utilized an observational analytic design with a cross-sectional approach. Extensive studies have explored the effects of learning and memorizing the Al-Quran on cognitive abilities in adults. In this study, cognitive function was evaluated by measuring serum BDNF levels and the MOCA-INA score. The study involved ۸۸ adult participants aged ۱۸-۳۰ years who met the inclusion and exclusion criteria. The BDNF levels in the ۱۱-۲۰ juz group (۴۵۵۴۰.۲۵ ± ۱۱۶۶۱.۸۴ pg/mL) and the ۲۱–۳۰ juz group (۴۶۰۰۵.۶ ± ۷۳۰۴.۸۶ pg/mL) were significantly higher than those in the <۱۰ juz group (۳۷۴۱۴.۸۸ ± ۱۰۲۲۹.۶۳ pg/mL). The difference between Quran memorization and BDNF levels was statistically significant (p = ۰.۰۰۲). However, the MOCA-INA scores did not show a significant difference across the three groups (p = ۰.۶۹۶). The amount of Al-Quran memorized is significantly associated with serum BDNF levels. Memorizing the Al-Quran may provide cognitive benefits, particularly in enhancing brain neurotrophic factors, and could be a beneficial practice for improving cognitive function in Muslims.

کلیدواژه ها:

BDNF ، cognitive ، memorizing Al-Quran ، MoCA-Ina