The Effect of a Single About of Resistance Exercise with Two Intensities and Different Recovery on Pro-Inflammatory Factor TNF-Α, HSP-۷۰, And Anti-Inflammatory Factor BDNF In Female Bodybuilders

Background and purpose: resistance exercises with high loads of HLRT can cause physiological changes, including in the immune system. The purpose and credibility of qualitative research investigated the effect of a resistance activity session with two different intensities and recovery on the expression of TNF-α, HSP-۷۰, and BDNF genes in female bodybuilders.Methods: In this Quasi-experimental study, twelve healthy female bodybuilders (age ۳۰±۵) volunteered to participate in the research. The samples performed one weekly strength training protocol session designed at two intensities of one maximum repetition in two different recovery times of one and two minutes. ۳۶ hours after the end of the training, sampling was done after ten hours of fasting, and the samples were centrifuged and stored at minus ۲۰℃. At the end of the four stages, the levels of TNF-α, HSP-۷۰, and BDNF were checked in the medical laboratory. A consent form was obtained from all the participants. SPSS version ۲۷ software was used for data analysis at a significance level of α ≤ ۰.۰۵.Findings: The results showed that HLRT resistance training compared to moderate intensity resistance training, by increasing the training intensity to ۸۵% of a maximum repetition and recovery time of one and two minutes, significantly reduced TNF-α level (with p<۰.۰۰۱and a significant increase in the serum levels of BDNF and HSP-۷۰ (with p<۰.۰۰۰۱).Conclusion: It seems that increasing the intensity of HLRT resistance training has no negative effect on the immune system, and probably with the decrease of the pro-inflammatory factor TNF-α and HSP-۷۰, the anti-inflammatory factor BDNF also increased reduces the incidence of inflammation in female bodybuilders.Background and purpose: resistance exercises with high loads of HLRT can cause physiological changes, including in the immune system. The purpose and credibility of qualitative research investigated the effect of a resistance activity session with two different intensities and recovery on the expression of TNF-α, HSP-۷۰, and BDNF genes in female bodybuilders.Methods: In this Quasi-experimental study, twelve healthy female bodybuilders (age ۳۰±۵) volunteered to participate in the research. The samples performed one weekly strength training protocol session designed at two intensities of one maximum repetition in two different recovery times of one and two minutes. ۳۶ hours after the end of the training, sampling was done after ten hours of fasting, and the samples were centrifuged and stored at minus ۲۰℃. At the end of the four stages, the levels of TNF-α, HSP-۷۰, and BDNF were checked in the medical laboratory. A consent form was obtained from all the participants. SPSS version ۲۷ software was used for data analysis at a significance level of α ≤ ۰.۰۵.Findings: The results showed that HLRT resistance training compared to moderate intensity resistance training, by increasing the training intensity to ۸۵% of a maximum repetition and recovery time of one and two minutes, significantly reduced TNF-α level (with p<۰.۰۰۱and a significant increase in the serum levels of BDNF and HSP-۷۰ (with p<۰.۰۰۰۱).Conclusion: It seems that increasing the intensity of HLRT resistance training has no negative effect on the immune system, and probably with the decrease of the pro-inflammatory factor TNF-α and HSP-۷۰, the anti-inflammatory factor BDNF also increased reduces the incidence of inflammation in female bodybuilders.

کلیدواژه ها:

Resistance training ، Brain-Derived Neurotrophic Factor ، HSP۷۰ Heat-Shock Proteins ، Tumor Necrosis Factor-alpha