Antibiotic Resistance of Non-Lactose-Fermenting Gram-Negative Bacteria in Urinary Tract Infections

The present study attempted to assess the resistance level of non-fermented Gram-negative bacteria in urine specimens to antibiotics targeting lactose sugar. A total of ۱۰۰ specimens of urine were obtained from individuals diagnosed with infections of urinary tract, divided into ۷۵ specimens for females and ۲۵ samples for males, and blood agar and macConky agar media were used to culture the samples in a manner. Plotting on the media and after the incubation period, ۸۵ isolates were obtained and divided into ۱۰ Gram-positive isolates and ۷۵ Gram-negative samples. ۲۰ out of ۷۵ isolates appeared non-fermenting for lactose, and the study extended from July ۲۰۱۸ to the end of ۲۰۱۸. The results showed that females are more susceptible to infection with non-lactose-fermenting bacteria in the urinary tract, as the total number of negative non-lactose-fermenting isolates taken from females was ۱۶ out of ۲۰, at a rate of ۸۰%, while the number of isolates taken from men’s samples was ۴ out of ۲۰ by ۲۰%. The results of the research showed the efficiency of some antibiotics in killing and inhibiting the growth of bacteria that do not ferment the sugar lactose, while some other antibiotics gave small rates of inhibition against this type of bacteria, as the antibiotic. Nitrofurantoin gave the highest rate of inhibition, reaching ۱۰۰%, while the antibiotic Ticarcillin gave a rate of ۴%.

کلیدواژه ها:

Urinary tract infections ، Lactose non-fermenting ، Escherichia coli