Effect of Laparoscopic Sleeve Gastrectomy on Hypothyroidism in Patients with Morbid Obesity: A one-year follow-up Prospective Cohort Study

Background & Objective: Obesity is a growing public health problem worldwide. Bariatric surgery is considered the safest and most effective therapeutic option, although it is associated with various metabolic and neurohormonal consequences. This study aims to evaluate the effect of sleeve gastrectomy (SG) on hypothyroidism within one year following surgery.Methods: In this single-center prospective cross-sectional study, patients with morbid obesity who were candidates for SG were included. Body mass index (BMI), levothyroxine dosage, and thyroid function tests were compared at baseline and ۱۲ months after surgery.Results & Conclusion: Patients’ BMI, levothyroxine dosage, TSH, and T۴ levels decreased significantly after surgery (P<۰.۰۰۰۱). The effect of SG on T۳ levels was not statistically significant. The results of this study demonstrate that SG can significantly improve thyroid function tests in patients with morbid obesity and reduce their need for levothyroxine within one year following surgery.

کلیدواژه ها:

Bariatric surgery ، Hypothyroidism ، Morbid obesity ، Sleeve gastrectomy