Quantitative and qualitative examination of kidney scintigraphy of normal White New Zealand rabbit after administration of saffron

Scintigraphy is a diagnostic and therapeutic technique in nuclear medicine. Its first applications in the ۱۹۷۰s involved imaging organs such as the brain, liver, spleen, etc. By the ۱۹۸۰s, radiopharmaceuticals were employed for diagnosing cardiac conditions. Today, nuclear medicine is recognized for its high accuracy in the diagnosis, prevention, and treatment of various diseases. Key advantages of nuclear medicine include rapid disease diagnosis, assessment of disorder extent, real-time evaluation of disease progression, and precise reporting on surgical outcomes for specific patients. Renal scintigraphy, also known as kidney scanning or imaging, is a valuable technique for assessing kidney function. This method utilizes radioisotopes to examine both the function and anatomy of the kidneys. Other methods for assessing kidney morphology include radiology, ultrasonography, MRI, and computed tomography; however, scintigraphy offers the unique advantage of physiological imaging. Given the previously demonstrated blood flow-enhancing effects of saffron, this study aims to quantitatively and qualitatively analyze the kidneys of four healthy New Zealand White rabbits using the radiopharmaceutical ۹۹mTc-DTPA. We will investigate and compare overall and individual GFR, peak times, and other parameters before and after the administration of saffron extract. Results indicate an increase in GFR and a reduction in peak time following saffron extract use.

کلیدواژه ها:

Kidney ، New Zealand White rabbit ، Saffron ، Scintigraphy.