Challenges in the Management and Treatment of Acute Myeloid Leukemia Post-Liver-Transplantation: A Case Report

Liver transplantation is the leading treatment for liver cirrhosis, no matter the cause. Immunosuppressive drugs reduce organ rejection but increase cancer risk, including skin, colorectal, oral cancers and post-transplant lymphoproliferative disorders (PTLDs) like acute myeloid leukemia (AML). Most PTLD cases are linked to Epstein-Barr virus, with a ۲۰% risk after organ transplants. AML in transplant recipients is challenging, with risks like septicemia and high mortality, causing early death in about ۲۵% of cases. We are reporting a ۳۶-year-old man with AML, nine years after his liver transplant for cryptogenic cirrhosis. His youth and complex diagnosis make his case particularly interesting.

کلیدواژه ها:

Acute Myeloid Leukemia ، Liver Transplantation ، Cytomegalovirus Retinitis ، Immunosuppressive Agents