Nanotechnological Approach to Combating Pseudomonas aeruginosa: A Review Study

Antibiotic resistance is one of the most significant health challenges in treating bacterial infections, particularly against Pseudomonas aeruginosa, due to its ability to develop resistance to many common drugs, making treatment difficult. This review article explores nanotechnology approaches to combat this bacterium. Initially, the pathogenicity of Pseudomonas aeruginosa and the therapeutic challenges related to its antibiotic resistance are discussed. Then, the antibacterial properties of various nanoparticles, including carbon-based, polymeric, lipid, and metallic nanoparticles, are examined in relation to combating this bacterium. The use of nanoparticles in the treatment of antibiotic-resistant Pseudomonas aeruginosa infections offers numerous benefits, including enhanced therapeutic efficacy and reduced side effects. However, challenges such as nanoparticle toxicity, issues with scalable production, and their compatibility with the human body must also be considered. Overall, this study demonstrates that nanoparticles hold significant potential in fighting Pseudomonas aeruginosa, but further research is needed for their broader clinical application.

کلیدواژه ها:

Pseudomonas aeruginosa ، Nanoparticles ، Metallic nanoparticles ، Toxicity