The effect of exercise and nutrition on cancer: a review

Reduced physical function, incorporating exercise intolerance, physical inactivity and dependency, is a common consequence of cancer and its treatment. Most guidelines for cancer survivors suggest that physical activity and exercise should be an integral and continuous part of care for all cancer survivors. However, the full potential of exercise will be only realized with careful and considered individual prescription. Strong evidence supports the promotion of physical activity and exercise for adult cancer patients before, during, and after cancer treatment, across all cancer types, and including patients with advanced disease. Combined aerobic and resistance exercise training, targeting fitness and muscle function, may be particularly relevant in patients with cachexia and other wasting related syndromes. Evidence for the added value of providing nutritional support alongside exercise is emerging. Patient, family and professional beliefs about the value and benefits of physical activity and exercise all influence patients’ attitudes and motivation to participate in programmes.Diet and exercise are modifiable lifestyle factors known to have a major influence on metabolism. Clinical practice addresses diseases of altered metabolism such as diabetes or hypertension by altering these factors. Despite enormous public interest, there are limited defined diet and exercise regimens for patients with cancer. Nevertheless, the molecular basis of cancer has converged over the past ۱۵ years on an essential role for altered metabolism in cancer. However, our understanding of the molecular mechanisms that underlie the impact of diet and exercise on cancer metabolism is in its very early stages.

کلیدواژه ها:

diet ، supplementation ، physical activity ، exercise ، quality of life ، physical function ، healthy lifestyle ، cancer ، physical fitness ، Systematic review