Vitamin B۶ Impact on Pediatric Vomiting and Nausea in Gastroenteritis: A Case-Control Study in Southern Iran

Background: Vomiting and nausea are common symptoms of Gastroenteritis (GE) in children, and high statistics in emergency department visits. Vitamin B۶, which plays a significant role in preventing vomiting in pregnant women, is one of the options for controlling GE. This study examines the effect of pyridoxine (vitamin B۶) in children with GE.Method: The study population of this research was a case-control including all children aged ۶ months to ۱۲ years with mild to moderate dehydration who were admitted to the children's hospital in Bandar Abbas city between ۲۰۲۱ and ۲۰۲۲. The study included two groups: control and intervention. The intervention group consisted of patients aged ۶ months to ۱۴ years of both genders who received pyridoxine to manage nausea and vomiting based on thier weight.Results: A total of ۷۰ individuals were included in our study, of whom ۴۸.۵۷% were female and ۵۱.۴۳% were male. The percentage of dehydration in patients with gastroenteritis in the control group was ۶۴.۶±۱.۵۹%, while in the group treated with vitamin B۶, it was ۳۲.۶±۱.۴۶%. There was no significant correlation between the percentage of dehydration in the control and vitamin B۶-treated groups. Additionally, there was no significant correlation between the amount of fluid received and the mean length of hospital stay in both group.Conclusion: Pyridoxine drug was not effective in treating vomiting caused by acute gastroenteritis in children compared to the control sample. Although vitamin B۶ is effective in controlling inflammation, it was not able to reduce GE complications.

کلیدواژه ها:

Gastroenteritis ، Pediatric ، Pyridoxine ، vomiting