Dermoid Cyst Characteristics: A ۱۰-year Case Series Study from a Tertiary Care Public Medical Center

Background: Ovarian dermoid cysts or mature cystic teratomas, are pathologically defined as having at least two elements out of three germ cell layers (ectoderm, mesoderm, and endoderm) with different presentations. The present study describes the characteristics of ۱۴۸ patients with dermoid cyst. Materials and Methods: The present study is a case series study in Imam Hossein Medical Center, a public center located in Tehran, Iran on dermoid cyst patients who were operated on for ۱۰ years period. Results: The most common presenting symptom was abdominal pain ۵۱ (۳۴.۵%), and ۲۹ (۱۹.۶%) were asymptomatic. Cystectomy was done in ۱۱۰ (۷۴.۳%) patients and was the most frequent surgery. Most of the dermoid cyst cases revealed typical sonographic findings. ROMA was positive in all tested cases (۲۶ out of ۱۴۸) as the most common abnormal tumor marker followed by CA۱۹-۹ in ۴۳.۹% and CA۱۲۵ in ۱۴.۴ %. CA۱۲۵ was significantly increased in larger tumors (p=۰.۰۱۸). Conclusion: Different manifestations of dermoid cyst discussed in this study, can provide clues for better management of these patients and make it possible to distinguish it from malignancies and other diseases. Diversity and wide range in presentation, age of diagnosis, ultrasonic findings, and serum tumor marker level in dermoid cyst should always be considered.

کلیدواژه ها:

Dermoid Cyst ، Teratoma ، Tumor Markers ، Ovarian cyst