Particle separation in a microchannel using tilted focus-ing standing surface acoustic wave

Acoustic particle separation is a promising active bioparticle separation with various func-tionalities. The importance of particle isolation and separation in chemotherapy and diagno-ses tends scientists to conduct vast research on this subject. Irrespective of all efforts there are two major drawbacks to acoustic separators. The first one is the particle separation distance and the latter is minor throughput. In this article, we proposed a tilted angled focused stand-ing acoustic wave that enhanced both parameters. The particle separation lateral displacement in our approach is improved and got more than two-fold from ۲۳ μm to ۴۶ μm at a ۰.۶ m/s flow rate. In this work, we proved our concept through numerical simulation of experimental research. The numerical simulation in COMSOL Multiphysics software provides better in-sight into the functionality of acoustic separators and it is helpful in the cost reduction of lab-on-chip devices. So by validation of our simulation, a new particle separator is presented.

کلیدواژه ها:

Acoustic separation ، Acoustophoresis ، Particle separation ، Cell separation.