Hysteroscopic Myomectomy and Reproductive Outcome

Background& Objective: Although hysteroscopic myomectomy as a safe and effective intervention is recommended for myoma resection, its effect on infertile patients who need the ICSI or IUI is not clearly defined. The present study was conducted aimed to evaluate the effect of hysteroscopic myomectomy on the outcome of pregnancy in in infertile patients who were candidates for IUI, ICSI, and FET cycles.Materials & Methods: In this cohort study, ۳۳۰ women underwent hysteroscopic myomectomy, of them ۲۰۴ patients had history of infertility and ۱۵۴ were candidates for ICSI cycles, ۳۳ for FET cycles, and ۱۷ for IUI cycles  at two tertiary teaching hospital and Royan institute between February ۲۰۰۸-February۲۰۱۲. Primary outcomes were chemical and clinical pregnancy rates.Results:  Among ۲۰۴ patients with a history of infertility, ۱۱۶ (۷۵.۴%) had primary and ۳۸ (۲۴.۶%) secondary infertility. In ICSI group, ۱۲۹ patients had one myoma, ۱۸ cases two myoma, ۵ cases three myoma and ۲ cases had five intracavitary myoma. In FET group, there were ۲۷ cases with one and ۶ cases with two intracavitary myoma. In IUI group, there were ۱۵ cases with one and two cases with two intracavitary myoma. In the ICSI group, there were ۱۷% clinical pregnancy, ۱% missed abortion, ۴% blighted ovum, and ۲% chemical pregnancy. In FET group, the clinical pregnancy was detected in ۲۸.۶% of women including ۷ clinical pregnancy, one blighted ovum and one chemical pregnancy. In IUI group, pregnancy failure rate was ۱۰۰%.Conclusion: Hysteroscopic myomectomy in addition to a safe and effective intervention for myoma resection, can improve pregnancy outcomes in infertile women.

کلیدواژه ها:

Submucosal Myoma ، Hysteroscopy ، myoma resection ، Pregnancy Outcome ، infertility