Construction of a New Silica-Based Nano-Hybrid Catalyst and Its Usage to Manufacture Bis(۶-Amino-۱,۳-Dimethyluracil-۵-Yl) Methanes

Initially, a novel inorganic-organic nano-hybrid catalyst titled Si-propyl-functionalized N۱,N۱,N۲,N۲-tetramethylethane-۱,۲-diamine-N۱,N۲-diium chloride dihydrogen phosphate grafted with nano-silica (SPTCDS) was constructed, and its structure was verified by the following analyses: (i) X-ray diffraction (XRD), (ii) FT-IR, (iii) field emission scanning electron microscopy (FE-SEM), (iv) thermogravimetry (TG), differential thermal gravimetric (DTG), and (v) energy-dispersive X-ray spectroscopy (EDX). In the present study, effectual solvent-free fabrication of bis(۶-amino-۱,۳-dimethyluracil-۵-yl) methanes was accomplished using SPTCDS; in this protocol, ۶-amino-۱,۳-dimethyluracil (۲ eq.) that reacted with aryl aldehydes (۱ eq.) to manufacture the uracil derivatives in satisfactory yields and reaction times.

کلیدواژه ها:

Bis(۶-amino-۱ ، ۳-dimethyluracil-۵-yl) methane ، Nano-hybrid catalyst ، Solvent-free ، Si-propyl-functionalized N۱ ، N۱ ، N۲ ، N۲-tetramethylethane-۱ ، ۲-diamine-N۱ ، N۲-diium chloride dihydrogen phosphate grafted with nano-silica