Association between Transient Tachypnea of the Newborn and Serum Vitamin D Levels in Infants and Mothers in Natural Childbirth

Background: Transient Tachypnea of the Newborn (TTN) is one of the most common causes of respiratory distress, shortly after birth, and is generally a benign, self-limited condition. Meanwhile, a lot of studies have linked vitamin D (VitD) levels with probably contributing to neonatal lung development.Methods: This study aimed to assess whether the serum levels of VitD are associated with TTN in infants and mothers in natural childbirth. This descriptive-analytical research was performed on ۳۹ infants with TTN and their mothers and ۳۹ control infants and their mothers referred to Motazedi hospital in Kermanshah University of Medical Sciences. Serum concentrations of VitD were measured in the first ۱۲-۲۴ h of postnatal age in both infants and mothers.Results: In the present study, no significant difference was found between healthy and TTN groups in terms of gender, mother's education level, drug use, asthma, diabetes, ۱th min Apgar score, mother's age, birth weight, and birth height. But, there was a significant difference between the two groups of control and intervention in terms of ۵th min Apgar score, and birth order. The mean levels of serum VitD were significantly lower in both TTN neonate patients and mothers. The results of the Pearson correlation coefficient indicated that there is a significant relationship between serum VitD levels of mothers and term infants in both groups.Conclusion: We observed that maternal VitD levels can be preventive for the development of TTN in infants through improving respiratory distress, and potentially shortening the duration of tachypnoea in natural childbirth.

کلیدواژه ها:

Natural Childbirth ، respiratory distress ، Term newborns ، Transient Tachypnea of the Newborn ، Vitamin D