Production and Evaluation of Uniform Magnetic T-۲ Imprinted Polymer from Aqueous Medium

Introduction: Mycotoxins are harmful secondary metabolites produced by fungi on agricultural products under various climatic conditions. In this study, we developed a method for the extraction and preconcentration of T-۲ toxin from aqueous media using magnetic molecular imprinting polymers. This technique involves creating polymers with high recognition properties for specific molecules and has been widely utilized in diverse scientific and technical applications. The objective of the study was to assess the binding properties of the magnetic MIPs for T-۲ extraction and determine their potential as an efficient sample preparation technique.Materials and Methods: Magnetic T-۲ imprinted nanoparticles using T-۲ toxin (T-۲) as the template, along with Methacrylic acid and ethyleneglycoldimethacrylate as the functional monomer and cross-linker were synthesized in aqueous media and characterized. We investigated their selective adsorption ability, adsorption kinetics, and isotherms. The selective extraction of T-۲ toxin from aqueous media was performed.Results: Our findings showed that under ambient conditions, the magnetic molecularly imprinted polymer nanoparticles (MMIP NPs) successfully extracted ۷۰% to ۸۱% of the T-۲ toxin from the aqueous media after three times of recycling.Conclusions: This study developed a method to create uniform magnetic T-۲ imprinted nanoparticles. The technique holds promise for detecting and analyzing T-۲ contamination in food and feed products. Magnetic molecularly imprinted nanoparticles have several advantages, including selective recognition, stability, reusability, and enhanced sensitivity.

کلیدواژه ها:

Uniform Magnetic Molecularly Imprinted Nanoparticle ، T-۲ toxin ، Relative Standard Deviation ، Adsorption Kinetic ، Adsorption Isotherm