Study of Clinical Profile and Immediate Outcome of Congenital Heart Disease in Neonates at a Tertiary Care Hospital in India: A Single Center experience

Background: Data on congenital heart diseases in neonates, especially critical congenital heart disease, varies worldwide. Developing countries have higher mortality than developed countries. To study the clinical profile of congenital heart diseases in neonates.Methods: Prospective observational study. Neonates admitted to a tertiary care hospital with congenital heart disease. Clinical details, investigations, and management of neonates admitted to a tertiary care hospital were studied prospectively.Results: Among the study neonates, ۶۰% had acyanotic heart disease, the most common being ASD, while ۴۰% had cyanotic heart disease, the most common being TGA—outborn cases comprised ۶۰% of the total neonates. The most common presenting features were fast breathing and cyanosis; the most common clinical sign was murmur(۵۹%). Among the study neonates, ۱۵ cases had low calcium levels. Definitive surgery was done in ۲۱ neonates, of which ۷ succumbed. The staged repair was done in ۹ neonates, of which ۲ succumbed. Of ۱۲ TGA cases,۱۰ underwent definitive repair, and ۷ did well at follow-up. Among the ۱۰ TOF babies, ۶ underwent staged repair. Out of the ۷ cases of CoA, ۶ underwent definitive surgery, and ۱ expired. Among Critical CHD, mortality was ۲۳.۳%.Conclusion: The most common cyanotic heart disease was ASD, and the most common cyanotic heart disease was TGA. Surgery was done in ۳۰ cases, out of which ۹ succumbed, and mortality among surgical cases was ۳۰%. At follow up TGA  cases with definitive surgeries were doing well. Mortality was lower compared to other studies in India. Hypocalcemia was observed in ۱۶.۶% of the CHD cases, which needs to be studied in the future.

کلیدواژه ها:

Cardiac murmur ، Cardiac surgical procedures ، Congenital ، cyanosis ، Heart Defects ، Neonates