The Effect of Eight Weeks of Endurance Training and Curcumin Supplementation on the Levels of Inflammatory Markers and Cardiopulmonary Function of Obese Girls with a History of Coronavirus Infection

Background: This study aimed to investigate the discrete and combined effects of ۸ weeks of endurance training and curcumin supplementation on the levels of inflammatory markers and pulmonary function in obese girls with a history of coronavirus infection.Methods: This research was conducted by semi-experimental method and clinical trial in the form of pre-test and post-test. ۴۰ obese women were selected randomly and allocated into ۴ groups: exercise+curcumin supplement (Curcu+Exe), exercise+placebo (Exe), curcumin supplement (Curcu), and control (Control). The subjects in exercise groups participated in an eight-week aerobic exercise program. The subjects of the supplement groups took three to four capsules every day. The level of blood serum inflammatory indicators was measured using the ELISA kit. The pulmonary function indices were evaluated using a spirometer.Results: The results of the present study showed that eight weeks of progressive endurance training along with curcumin supplementation in obese girls with a history of corona infection, led to a decrease in inflammatory indicators (IL-۶ and TNF-a) and improved pulmonary function indicators in the experimental groups.Conclusions: Curcumin supplementation along with progressive endurance exercises can lead to the improvement of inflammatory conditions and pulmonary function in obese girls with a history of corona disease. Therefore, these people can improve their body composition and general health through the combination of endurance activity and curcumin supplementation.Background: This study aimed to investigate the discrete and combined effects of ۸ weeks of endurance training and curcumin supplementation on the levels of inflammatory markers and pulmonary function in obese girls with a history of coronavirus infection. Methods: This research was conducted by semi-experimental method and clinical trial in the form of pre-test and post-test. ۴۰ obese women were selected randomly and allocated into ۴ groups: exercise+curcumin supplement (Curcu+Exe), exercise+placebo (Exe), curcumin supplement (Curcu), and control (Control). The subjects in exercise groups participated in an eight-week aerobic exercise program. The subjects of the supplement groups took three to four capsules every day. The level of blood serum inflammatory indicators was measured using the ELISA kit. The pulmonary function indices were evaluated using a spirometer. Results: The results of the present study showed that eight weeks of progressive endurance training along with curcumin supplementation in obese girls with a history of corona infection, led to a decrease in inflammatory indicators (IL-۶ and TNF-a) and improved pulmonary function indicators in the experimental groups. Conclusions: Curcumin supplementation along with progressive endurance exercises can lead to the improvement of inflammatory conditions and pulmonary function in obese girls with a history of corona disease. Therefore, these people can improve their body composition and general health through the combination of endurance activity and curcumin supplementation.

کلیدواژه ها:

IL-۶ ، TNF-a ، Obesity ، Physical activity ، COVID-۱۹