Clinical Factors Associated with Maternal Death in Pregnant Women Infected by COVID-۱۹ in Indonesia: A Multicenter National Study

سال انتشار: 1404
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 75

فایل این مقاله در 11 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

JR_JOGCR-10-1_002

تاریخ نمایه سازی: 11 دی 1403

چکیده مقاله:

Background and Objective: The aim of this study is to evaluate the clinical risk factors associated with maternal death in pregnant women infected by COVID-۱۹.Methods: This is a multicenter prospective study in Indonesia, included all pregnant women with confirmed COVID-۱۹. Participants were divided into two groups based on the final outcomes: maternal death group and survived group. The main outcomes evaluated were: maternal background, clinical risk factors, comorbidities, clinical characteristics, and laboratory results.Results: There were ۸۹ participants in the maternal death group and, ۱۶۷۳ in the survived group. The maternal death group have an older maternal age (۳۲ vs ۳۱ years old, p=۰.۰۳) and earlier gestational ages during admission (۳۳ vs ۳۷ weeks, p=۰.۰۰۰). The maternal death group have a significantly higher rate of cardiac disease (۶.۵% vs ۱.۲%, p=۰.۰۰۴), acute kidney injury (۵.۲% vs ۰.۳%, p=۰.۰۰۰), coinfections (۲۹.۹% vs ۱۰.۸%, p=۰.۰۰۰), and anemia (۱۴.۳% vs ۶.۷%, p=۰.۰۱۲). The maternal death group have a higher level of maternal blood leukocyte (۱۳۹۷۰ vs ۱۰۳۴۵), netrofil ۷۵.۷ vs ۷۰), ALT (۴۷ vs ۲۳), AST (۲۶ vs ۱۹), CRP (۳۷.۴ vs ۰.۷), and procalcitonin (۰.۲۷ vs ۰.۰۶) (p<۰.۰۵). The risk factors that independently related to maternal death are fever (Exp(B): ۱۲.۸۴۷, ۹۵% CI: ۵.۶۳۸-۲۹.۲۷۷; p=۰.۰۰۰), pneumonia from chest x-ray (Exp(B): ۲.۵۲۴, ۹۵% CI: ۱.۱۶۳-۵.۴۷۹; p=۰.۰۱۹), and ICU admission (Exp(B): ۴۹.۴۳۰, ۹۵% CI: ۲۱.۰۲۴-۱۱۶.۲۱۵; p=۰.۰۰۰).Conclusion: Our research indicates that the presence of fever, pneumonia, and ICU hospitalization are independently associated with maternal death in COVID-۱۹-infected pregnant women.

نویسندگان

Muhammad Ilham Akbar

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Universitas Airlangga Hospital, Surabaya, Indonesia

Rima Irwinda

Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia

Julian Dewantiningrum

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi General Hospital, Semarang, Indonesia

Nuswil Bernolian

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sriwijaya, Dr. Muhammad Hoesin General Hospital, Palembang, Indonesia

Makmur Sitepu

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sumatera Utara, Dr. H. Adam Malik General Hospital, Medan, Indonesia

Maisuri Chalid

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hassanudin, Dr. Wahidin Sudirohusodo General Hospital, Makassar, Indonesia

Mukhamad Noryanto

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Brawijaya, Dr. Saiful Anwar General Hospital, Malang, Indonesia

Cut Yeni

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Syiah-Kuala, Dr. Zainoel Abidin General Hospital, Aceh, Indonesia

John Wantania

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sam Ratulangi, Prof. Dr. Kandou General Hospital, Manado, Indonesia

Anak Agung Raka Budayasa

Department of Obstetrics and Gynecology, Sanjiwani General Hospital, Gianyar Bali, Indonesia

Muhammad Aziz

Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjajaran, Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

مراجع و منابع این مقاله:

لیست زیر مراجع و منابع استفاده شده در این مقاله را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود مقاله لینک شده اند :
  • World Health Organization (WHO). WHO Coronavirus (COVID-۱۹) Dashboard | WHO ...
  • United Nations Children's Fund (UNICEF). Indonesia COVID-۱۹ Response Situation Report ...
  • World Health Organization (WHO). Indonesia WHO Coronavirus Disease (COVID-۱۹) Dashboard ...
  • Peta Sebaran. COVID-۱۹.go.id [Internet]. ۲۰۲۲. Available from: [https://covid۱۹.go.id/peta-sebaran ...
  • Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S, ...
  • Akbar MIA, Gumilar KE, Andriya R, Wardhana MP, Mulawardhana P, ...
  • Villar J, Ariff S, Gunier RB, Thiruvengadam R, Rauch S, ...
  • Thoma ME, Declercq ER. All-Cause Maternal Mortality in the US ...
  • Fatmaningrum DA, Anis W, Laksana MAC. The impact of the ...
  • Brown MA, Magee LA, Kenny LC, Karumanchi SA, McCarthy FP, ...
  • Tranquilli AL, Dekker G, Magee L, Roberts J, Sibai BM, ...
  • ACOG. Postpartum Hemorrhage. ۲۰۲۲ ...
  • Lopes JA, Jorge S. The RIFLE and AKIN classifications for ...
  • WHO. Haemoglobin concentrations for the diagnosis of anaemia and assessment ...
  • Erez O, Othman M, Rabinovich A, Leron E, Gotsch F, ...
  • Vouga M, Favre G, Martinez-Perez O, Pomar L, Acebal LF, ...
  • Allotey J, Stallings E, Bonet M, Yap M, Chatterjee S, ...
  • Sharma R, Seth S, Mishra P, Mishra N, Sharma R, ...
  • Ruan Q, Yang K, Wang W, Jiang L, Song J. ...
  • Wardiana M, Prakoeswa CRS, Astari L, Budi Prasetyo B, Hidayati ...
  • Barkley JS, Kendrick KL, Codling K, Muslimatun S, Pachón H. ...
  • Beckert RH, Baer RJ, Anderson JG, Jelliffe-Pawlowski LL, Rogers EE. ...
  • La Verde M, Riemma G, Torella M, Cianci S, Savoia ...
  • Wardhana MP, Maniora MC, Aryananda RA, Gumilar KE, Wicaksono B, ...
  • Porta-Etessam J, Núñez-Gil IJ, González García N, Fernandez-Perez C, Viana-Llamas ...
  • Mehta P, McAuley DF, Brown M, Sanchez E, Tattersall RS, ...
  • Ouyang SM, Zhu HQ, Xie YN, Zou ZS, Zuo HM, ...
  • Atak Z, Ocakoğlu SR, Uyanıklar Ö, Üstünyurt E. The effect ...
  • Lombardi A, Duiella S, Li Piani L, Comelli A, Ceriotti ...
  • Covali R, Socolov D, Socolov R, Pavaleanu I, Carauleanu A, ...
  • Aldika Akbar MI, Gumilar KE, Tjokroprawiro BA, Ulhaq RA. Successful ...
  • Demelo-Rodríguez P, Cervilla-Muñoz E, Ordieres-Ortega L, Parra-Virto A, Toledano-Macías M, ...
  • Prochaska E, Jang M, Burd I. COVID-۱۹ in pregnancy: Placental ...
  • Chavan M, Qureshi H, Karnati S, Kollikonda S. COVID-۱۹ Vaccination ...
  • Donders GGG, Grinceviciene S, Haldre K, Lonnee-Hoffmann R, Donders F, ...
  • Lv D, Peng J, Long R, Lin X, Wang R, ...
  • Cavanaugh AM, Spicer KB, Thoroughman D, Glick C, Winter K. ...
  • Huang YZ, Kuan CC. Vaccination to reduce severe COVID-۱۹ and ...
  • Lopez Bernal J, Andrews N, Gower C, Robertson C, Stowe ...
  • Akova M, Unal S. A randomized, double-blind, placebo-controlled phase III ...
  • نمایش کامل مراجع