Assessing the effects of Zinc supplementation on the treatment ofinfertility in women with polycystic ovary syndrome (PCOS): review article

Objective(s): PCOS affects about ۱۰ percent of women in the childbearing age and is one ofthe most common causes of infertility. Hence, Present study was conducted to evaluate theeffect of Zinc supplementation on the successful induction of ovulation in infertile womenwith PCOS.Method: Searching for information sources (SID, Science Direct, Google Scholar, SCOPUS,PubMed) was carried out on conducted studies in the past decade .Words PCOS, infertility,Zinc were used as key words and after removal of repetitive and common articles of databases,۳۴ articles were obtained. Subsequently, by a closer look at the titles and objects of them,the results of ۱۵ related articles were extracted.Results: Some reviewed articles showed women with PCOS significantly have lower serumzinc levels and in women with PCOS, zinc supplementation has a positive effect on manyparameters, especially those related to insulin resistance and lipid balance.Conclusion: Given the prevalence of Zinc and the possible role of Zinc supplement inimprovement of ovulation, further studies are necessary to determine the exact duration anddosage of this supplements in PCO patients

کلیدواژه ها:

PCOS ، infertility ، zinc ، anovulation ، insulin resistance.