Vitamin D Deficiency as a Risk Factor for Gestational Diabetes Mellitus

Introduction: Gestational diabetes mellitus (GDM) is a common complication affecting around ۱۳.۵% of pregnancies globally. This condition, characterized by insulin resistance and glucose metabolism disturbances, may be linked to vitamin D deficiency. A recent study aimed to investigate this potential connection to enhance prevention and treatment strategies. Material and methods: From ۲۰۱۹ to ۲۰۲۰, a cohort study was conducted to assess the prevalence of vitamin D deficiency in pregnant women with GDM across different clinical settings. Participants were categorized based on their vitamin D status, excluding those with unclear levels or a history of diabetes. Precise diagnostic criteria were established, and data analysis was carried out using SPSS software. Results: from the study of ۱۰۰ pregnant women revealed a significant association between vitamin D deficiency and GDM. Those deficient in vitamin D, with an average age of ۲۸.۸۲ years and weight of ۷۳.۲۰ kg, showed higher rates of GDM compared to those with sufficient vitamin D levels (average age: ۳۰.۵۲ years, weight: ۷۸.۵۹ kg). This correlation was particularly notable among women aged ۲۶ to ۳۵ and those with normal or high body mass index (BMI). No significant associations were found with comorbidities, parity, or gravidity. Discussion and Conclusion: Study shows ۳۲% higher risk of GDM with low vitamin D levels vs normal levels (۴%), especially in ۲۶-۳۵ age group. Larger, multi-center studies needed to confirm and build upon these findings due to limitations like sample size and regional scope.

کلیدواژه ها:

Vitamin D ، Gestational diabetes mellitus ، Maternal health ، BMI