Impact of Vitamin D Deficiency on Pregnancy Outcomes in Iranian Women: An Observational Study in ۲۰۲۰-۲۰۲۱

Abstract Introduction: Vitamin D deficiency in pregnancy can lead to pre-eclampsia, gestational diabetes and preterm delivery. Adequate vitamin D intake from supplements and sunlight is essential, but careful monitoring is required to avoid toxicity. Further research is needed to fully understand the effects of vitamin D on pregnancy. Materials and methods: A study with a sample size of ۷۳ individuals investigated the relationship between vitamin D levels and pregnancy outcomes. The study included ۱۴۸ pregnant women with normal or low vitamin D levels. Previous research suggests a significant prevalence of vitamin D insufficiency in pregnant women. The effects of maternal vitamin D status on both the foetus and the mother were the focus of the study. Results: The results of the current study showed that the mean age of the mothers in the normal vitamin D group was ۳۰.۰۰±۴.۹۸ years and in the vitamin D deficient group it was ۲۹.۳۳±۵.۴۹ years. The results show that there is no significant relationship between maternal age and vitamin D level. Also gravidity, parity, number of live births, gestational age and pre-eclampsia were not significantly associated with vitamin D deficiency. While preterm birth, gestational diabetes and preterm rupture of membranes were significantly more common in people with vitamin D deficiency. Discussion and conclusion: Insufficient vitamin D levels are associated with adverse pregnancy outcomes. Insufficient levels increase the risk of preterm birth, pre-eclampsia, gestational diabetes, premature rupture of membranes, miscarriage and stillbirth. Maintaining optimal levels is essential. More research is needed on prevention strategies.

کلیدواژه ها:

Vitamin D ، Pregnancy ، Vitamin D deficiency ، Gestational diabetes ، Preeclampsia