Synthesis and Antibacterial Evaluation of Zinc Sulfide/Chitosan Nanocomposites for Biomedical Applications

Nanomaterials play a crucial role in addressing bacterial infection, which are growing concern. To address this pressing issue this research explores the creation and antibacterial properties of Zinc Sulfide/Chitosan nanocomposite marking a frontier in applications. The production and analysis of these nanocomposites were thoroughly examined using XRD, FTIR, FESEM, EDX elemental mapping, and Antibacterial (Colony Count method) techniques. As per the XRD findings, ZnS/CS nanoparticles were synthesized with crystalline structures of chitosan and hexagonal ZnS featuring an average crystal size ranging from ۳۰ to ۴۰ nm. The FTIR spectrum unveiled the groups and bonding characteristics of the produced nanoparticles affirming the synthesis and potential stabilization mechanisms. FESEM imaging provided an inspection of the surface morphology revealing a shape with a particle size distribution around ۲۱۲ nm for the nanocomposite and EDX In order to evaluate the composition and prove the presence of elements in the nanocomposite. Moreover, the antibacterial efficacy against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria was assessed. The outcomes indicated that ZnS nanoparticles and ZnS/CS nanocomposite displayed enhanced potency compared to CS and ZnS alone. These results underscore the potential of the developed samples to offer insights in applications presenting promising pathways, for combating bacterial infections and advancing biomedical technology.

کلیدواژه ها:

Nanocomposite ، co- precipitation ، Zinc Sulfide ، Chitosan ، Antibacterial activity