Incorporation of Phosphate into Layered Double Hydroxide as the Additive for Calcium Silicate Cement

Calcium silicate cement (CSC) has emerged as a promising material in the field of bone tissue engineering due to its biocompatibility, bioactivity, and osteoconductivity. CSC has been extensively used in endodontic procedures for its excellent sealing properties and ability to promote tissue repair. On the other hand, layered double hydroxides (LDHs) are a class of materials that have shown great promise in the field of bone tissue engineering. LDHs are composed of positively charged layers with intercalated anions, such as phosphate, which mimic the mineral composition of natural bone. This study outlines the synthesis procedure for calcium silicate cement incorporating phosphate-intercalated layered double hydroxide as an additive for bone regeneration. LDH was synthesized via a hydrothermal process at ۱۴۰°C, while dicalcium silicate was prepared using the sol-gel technique. The resulting hybrid material was characterized using XRD analysis, FTIR spectroscopy, SEM, and EDS analysis, confirming the presence of MgCaAl LDH and beta-dicalcium silicate phases. The EDS analysis showed characteristic peaks corresponding to the elemental composition, indicating successful intercalation of phosphate and suggesting significant potential for applications in bone tissue engineering.

کلیدواژه ها:

Calcium silicate cement ، Layered double hydroxides ، Phosphate ، bone regeneration