Nature’s Web: Natural Polymers in Electrospinning Nanofibers for Tissue Engineering

Electrospinning is a promising technique for creating nanofibrous scaffolds that mimic the extracellular matrix (ECM). These scaffolds offer significant potential in tissue engineering and wound healing applications. By incorporating natural polymers such as collagen, chitosan, alginate, and elastin, electrospinning combines the biocompatibility, biodegradability, and inherent biological functions of these materials with the structural advantages of electrospun fibers.The resultin nanofibrous scaffolds provide a conducive environment for cellular adhesion, proliferation, and migration, promoting effective tissue regeneration. Recent advancements in electrospinning techniques have enabled the creation of multifunctional scaffolds incorporating antimicrobial agents, growth factors, and other bioactive molecules, enhancing their therapeutic potential. However, challenges such as poor mechanical properties of natural polymers, limited solubility, and issues with scaffold architecture and cellular infiltration remain. This mini-review explores the current state of electrospinning natural polymers for wound healing, highlighting the unique properties, challenges, and future directions in this rapidly evolving area of research. By leveraging the adaptability of electrospinning and the bioactivity of natural polymers, this technology holds great promise for developing advanced, sustainable solutions for regenerative medicine.

کلیدواژه ها:

Natural polymers ، electrospinning ، wound healing ، nanofibers