A review of the treatment of some medicinal plants against Helicobacter pylori

Helicobacter pylori is a type of bacteria that infects the stomach. It can damage the tissue of the stomach and the duodenum, the first part of the small intestine. Known as H. pylori, this bacterium can cause inflammation, leading to redness and pain. In some cases, it results in painful ulcers in the upper digestive tract. H. pylori is very common and affects many people. Most individuals with this infection do not experience symptoms or harm. However, it is important to know that H. pylori is the primary cause of stomach ulcers. Globally, H. pylori is recognized as the primary cause of peptic ulcers and gastric cancer. It is estimated that around ۵۰ percent of the global population is infected with H. pylori. However, treatments aimed at eradicating the bacteria have often failed due to various factors, including the development of antibiotic resistance. This has led to a pressing need for new medications targeting H. pylori, prompting a search for alternative, more effective, and safer inhibitors. In contemporary drug development, medicinal plants are being proposed as sources of new synthetic compounds. These plants are considered environmentally friendly, straightforward, safer, quick, and less toxic compared to traditional treatments. This review aims to emphasize the anti-H. pylori properties of medicinal plants, their secondary metabolites, and their mechanisms of action, with the goal of documenting these plants before they are lost to changing cultures and traditions. In this review study, the effects of some medicinal plants and compounds within plants on H. pylori have been investigated until ۲۰۲۴.

کلیدواژه ها:

Helicobacter pylori ، antibiotic resistance ، medicinal plants.