Comparing The Effects of Palm Pollen with Letrozole+ Tamoxifen in Infertile Woman with Polycystic Ovary Syndrome on Pregnancy Rate

Background: polycystic ovary syndrome (PCOS), one of themost common causes of infertility due to anovulation, affects۴-۷% of reproductive women. The aim of this research is tocompare the effect of palm pollen with letrozole + tamoxifenon pregnancy rate as treatment of infertile polycystic ovary syndromewomen in Jahrom city.Materials and Methods: This comparative clinical trial wasdone on ۳۰ infertile PCOS women referred to Dr.rasekh clinicwith aged ۱۸-۴۲ years. patients were randomly allocatedto either case or control group. The control group prescribedletrozole + tamoxifen and Case group palm pollen from thirdto eighth day of menstrual cycle .Transvaginal ultrasound parametersincluding Ovarian follicular size , numbers and endometrialthickness were measured during treatment and based ofthis parameters continue these regimens and prescribed triggerdrug.Results: Endometrial thickness in palm pollen groups andtamoxifen+letrozole groups had significant difference in firstvisit (P<۰.۰۱۹) respectively but no significant difference in thesecond and third visit in two groups. In the first visit, there wasa significant difference in the size of left ovarian follicles incase and control group(P<۰.۰۰۴) ,but in the second and thirdvisit, the left ovarian follicle size in case group was larger thancontrol group, without significant difference statistically. In thefirst visit, there was a significant difference in the size of rightovarian follicles in case and control group(P<۰.۰۰۱) but, no significantdifference in second and third visit. Pregnancy rate washigher in the group using palm pollen but there was no significantrelationship between two groups (P<۰.۶۲۴).Conclusion: Because of significant effects of palm pollen onincrease of endometrial thickness and size of dominant follicle,and eventually increase of pregnancy rates. Therefore, we recommend,this low costs, low side effect regimen in treatment ofPCOS patients.

کلیدواژه ها:

PCOS ، Palm Pollen ، Letrozole ، Tamoxifen ، Pregnancy Rate