Synthesis of carboxymethyl chitosan sulfate microparticles

Chitosan, despite its antimicrobial and antifungal properties, has poor solubility in aqueous solutions.This solubility can be improved through carboxymethylation. Carboxymethylchitosan(CMC) isbiodegradable, biocompatible, and retains antibacterial and antifungal activities.Carboxymethylchitosan sulfate(CMCS) offers superior properties, including antitumor effects,immune system stimulation, antiseptic, and enhanced antimicrobial properties. In this research,carboxymethyl chitosan sulfate microparticles were synthesized using the emulsion cross-linkingmethod, and the effect of varying concentrations of carboxymethyl chitosan sulfate on themorphology and size of the microparticles was investigated.

کلیدواژه ها:

Biopolymer microparticle ، Carboxymethyl chitosan sulfate ، emulsion crosslinking