Conductive Hydrogels with Photothermal and Antibacterial Activity forWound Healing

Developing conductive hydrogel dressings with multifunctions including antibacterial, radicalscavenging ability and good mechanical property to enhance full-thickness skin wound regenerationis highly desirable in clinical application. Herein, a series of antioxidant conductive photothermalantibacterial hydrogels based on using a radical polymerization system are prepared for wounddressing. These hydrogels exhibit high swelling, degradability, tunable rheological property, andsimilar or superior mechanical properties to human skin. Antioxidant activity, tissue adhesiveness,conductivity, and NIR irradiation enhanced in vitro antibacterial behavior of the hydrogels areinvestigated. In summary, these antioxidative conductive hydrogels with photothermal antibacterialproperty to promote complete skin regeneration are an excellent wound dressing for full-thicknessskin repair.

کلیدواژه ها:

Hydrogel ، Conductive ، Wound healing ، Photothermal ، Antibacterial