Synthesis and Characterization of Cellulose Nanocrystal-Grafted PolybutylAcrylate with the Potential of Drug Delivery Applications

In this study, polybutyl acrylate (PBA) grafted onto cellulose nanocrystals (CNCs) was synthesizedutilizing S-(thiobenzoylthioglycolic) acid as a reversible addition-fragmentation chain transfer(RAFT) agent. The grafting process involved two key stages: the initial attachment of the RAFT agentto the CNCs, followed by the polymerization of butyl acrylate on the CNC surface. The resulting CNCg-PBA composite was characterized using Fourier transform infrared spectroscopy (FTIR) andthermogravimetric analysis (TGA) to confirm the successful grafting. FTIR spectra revealedcharacteristic peaks indicating the presence of both CNC and PBA, while TGA provided insights intothe thermal stability and decomposition behavior of the composite. The resulting cellulose nanocrystalgraftedpolybutyl acrylate demonstrated promising characteristics for potential use in drug deliverysystems. Further studies are warranted to explore its applicability and efficiency in this domain.

کلیدواژه ها:

Polymer Synthesis and Characterization ، CNC ، RAFT ، Surface Modification ، Thermalstability