Development of a Dual Stimuli-responsive Polymers for TrackingTemperature

This study describes the development of a novel photo- and temperature-responsive copolymer,P(NIPAM-co-RBAC), synthesized using reversible addition-fragmentation chain transfer (RAFT)polymerization. The copolymer incorporates rhodamine B acrylate (RBAC) as a fluorophoremonomer to impart photoresponsive properties. This behavior arises from the combined effects ofthe RBAC moiety and the thermoresponsive nature of the poly(N-isopropylacrylamide) (PNIPAM)block. As the temperature increases, the copolymer undergoes a transition due to its lower criticalsolution temperature (LCST), leading to decreased solubility and a quantifiable reduction in emissionintensity. This ratiometric decrease in fluorescence intensity offers significant potential forP(NIPAM-co-RBAC) as a highly sensitive, noninvasive, real-time optical sensor for temperaturemonitoring in biological systems.

کلیدواژه ها:

Smart polymer ، Temprature sensor ، Photoresponsive polymer ، RAFT polymerization