Synthesis of bioadhesive, self-healing injectable hydrogel with photothermaltherapy effect based on dynamic borate ester for biomedical applications

Antibacterial hydrogels with injectable and self-healing properties have attracted much attention inthe field of wound dressings because they not only can prevent bacterial infections, but also meet thebasic needs for wound healing. However, how to achieve high antibacterial efficacy and low drugresistance for hydrogels is still a challenge. Herein, an injectable, self-healing,bioadhesive and nearinfrared(NIR) photosensitive hydrogel composed of polydopamine nano-particles(PDA NPs),polyvinyl alcohol (PVA) and borax is prepared. According to the obtained results, Polydopamineused in the composition of hydrogel, while increasing its biological adhesion, also causesphotothermal properties. Therefore it can be said that these hydrogels can be suitable candidates asa wound dressing for wound healing applications.

کلیدواژه ها:

Polymers in medicene and healthcare ، Photothermal ، Hydrogel wound dressing