The Effect of pH on the Degradation of Methacrylate Poly(glycerol sebacate)as a Photocurable Biopolymer

Poly(glycerol sebacate) (PGS) is a polymer used in biomaterial applications that has receivedsignificant attention in recent years. This elastomer is characterized by rapid biodegradability andbiocompatibility, along with suitable mechanical properties, making it ideal for tissue engineering.In this study, we present a curable form of PGS enhanced with methacrylate groups (PGS-M). Weproduced nerve guide conduits (NGCs) of PGS-M using the photopolymerization method withDigital Light Processing (DLP) to repair damaged peripheral nerves and investigated its degradationin Tris buffer at different pH levels over ۲۴ hours

کلیدواژه ها:

biopolymer ، poly(glycerol-sebacate) (PGS) ، PGS-Methacrylate ، degradation ، DLP ، Nerve guide conduits (NGCs)