Delving into the Role of α-Smooth Muscle Actin as a Predictive Biomarker of Early Recurrence in Invasive Ductal Adenocarcinoma of Breast

Dear Editor, I found the recent publication by Andrianto et al. (۱) in the Iranian Journal of Pathology, titled "α-Smooth Muscle Actin as Predictors of Early Recurrence in Early-Stage Ductal Type Breast Cancer After Mastectomy and Chemotherapy," intriguing. This study, employing a cross-sectional immunohistochemical approach, investigates the significance of α-smooth muscle actin (α-SMA) as a potential biomarker for early recurrence in invasive ductal adenocarcinoma (IDC) of the breast. In the current era of precision medicine, it is apt to be on the look for novel biomarkers in predictive oncology, especially in breast cancer which remains one of the leading causes of cancer-related mortality in women despite scientific advancements. However, it's crucial to thoroughly understand the scientific methodology to fully grasp the paper's findings and utilize the same in clinical practice or research settings.

کلیدواژه ها:

α-Smooth muscle actin ، biomarker ، Recurrence ، ductal adenocarcinoma ، Breast