Neuroscopy by magnetic resonance spectroscopy technique in the brain tumors: from clinical physics to chemical neuroimaging

Magnetic resonance imaging (MRI) is the basic method for brain tumor imaging. It is essential for every stage of patient care, from diagnosis and therapy planning to treatment response and/or recurrence assessment. Currently, brain cancers can be diagnosed and monitored more effectively thanks to neuroimaging, which can characterize both the morphologic and non-morphologic (functional, hemodynamic, metabolic, cellular, microstructural, and occasionally even genetic) aspects of the tumors. A unique magnetic resonance method called Magnetic resonance spectroscopy (MRS) is utilized to measure the various metabolites present in a tissue voxel, or volume pixel. In clinical settings, N-acetyl aspartate (NAA), choline (Cho), and creatine (Cr) are the primary metabolites in MRS. Necrosis and recurring brain tumors can be distinguished from one another using MR spectroscopy. Cho/NAA, Cho/Cr, and NAA/Cr ratios are considerably superior predictors of detecting recurring malignancies. As a result, the MRSI can be used to distinguish between tumor necrosis and recurrence.

کلیدواژه ها:

Brain tumor ، Neuroimaging ، Magnetic resonance spectroscopy ، Neuroscopy