Innovative Approaches in Advanced Bioreactor Design for Enhanced Disease Treatment in Biomedical Engineering

The advent of bioreactor technology signifies a transformative milestone in biomedical engineering, enabling the cultivation and manipulation of biologically active environments for disease treatment. This paper explores the intricate design considerations of bioreactors tailored for various medical applications. By analyzing cell culture, microbial, and tissue engineering bioreactors, we emphasize their crucial roles in advancing innovative therapies such as adoptive cell transfer for cancer and bioartificial organs for organ regeneration. Essential design factors, including sterility, nutrient provision, waste removal, scalability, and pivotal for optimizing bioreactor performance and ensuring efficient biopharmaceutical production. Additionally, we explore specific applications in neurological, urological, cardiological, and liver diseases, illustrating how bioreactors facilitate tissue engineering and drug screening. Emerging technologies such as ۳D bioprinting and organs-on-chips are set to revolutionize the field, enabling personalized therapies and accelerating drug discovery. Ultimately, this paper highlights the profound impact of bioreactor technology on the future of regenerative medicine and personalized healthcare

کلیدواژه ها:

Bioreactors ، tissue engineering ، stem cell manufacturing