Relationship between Vitamin D and Preeclampsia in Pregnant Women: A Comparative Descriptive Study

Aims: Pregnancy poisoning or preeclampsia is a serious and specific disorder of pregnancy that affects ۸% of the pregnant women. Similar studies conducted in this regard showed disagreement about the relationship between vitamin D deficiency and preeclampsia. Hence, the present study was conducted to evaluate the serum level of vitamin D in preeclampsia patients hospitalized in the maternity ward compared to healthy pregnant women. Instruments & Methods: This descriptive comparative study was conducted on ۱۸۰ pregnant women with a severe preeclampsia below the gestational age of ۳۳ weeks and ۲۰۰ non-preeclampsia pregnant women in Yasuj City from ۲۰۱۷ to ۲۰۱۹. Blood samples were taken from all subjects to measure vitamin D levels. The levels of ۲۵-hydroxy vitamin D were measured in the laboratory using the ELISA method. Data were analyzed using SPSS ۲۰ software. Findings: There was no significant difference between the preeclampsia group and healthy pregnant women in terms of mean levels of vitamin D (p=۰.۴۹). Preeclamptic women with normal level of vitamin D and vitamin D deficiency showed no significant differences in the mean of uric acid, systolic blood pressure, diastolic blood pressure, and the number of previous pregnancies (p>۰.۰۵). Conclusion: There is no relationship between serum vitamin D۳ levels and hypertensive conditions of pregnancy such as preeclampsia in pregnant women. Also, vitamin D۳ levels are insufficient in both groups.

کلیدواژه ها:

Preeclampsia ، Vitamin D ، Proteinuria ، Uric Acid