The Effect of Uterine Cooling During Cesarean Delivery on Blood Loss in Patients Undergoing Cesarean Section: A Randomized Controlled Trial

Background: Cooling the uterus during cesarean section has emerged as one of the non-pharmacological management for blood loss during cesarean section. The aim of this study was to evaluate the effect of uterine cooling during the cesarean section on decreasing postpartum hemorrhage.Methods: In this single-blinded randomized clinical trial, a sample of ۳۰۰ women with a singleton pregnancy, at ۳۷ to ۴۰ weeks gestation, who were scheduled for cesarean section, was divided into two groups of ۱۵۰ participants. In the intervention group after placental delivery, the uterus was covered with cold saline-soaked surgical sponges at ۰-۴°C at the time of hysterotomy repair, and the control group received standard cesarean section. The volume of blood loss, the hemoglobin level before surgery and ۲۴ h after surgery, the need for additional oxytocin therapy, and the incidence of adverse effects were recorded.Results: The bleeding volume and hemoglobin concentration reduction were significantly lower in the intervention group than in the control group (۲۶۰.۸۶± ۱۵۰.۲۵ Vs ۲۱۴.۳۵± ۸۳.۵۱, P<۰.۰۰۰۱ and ۱.۲۴±۰.۷۵ Vs ۱.۵۴±۰.۹۲, P = ۰.۰۰۷ respectively). There were no statistically significant differences between the two groups in the frequency of need for additional uterotonic drugs. (۱۸% vs. ۲۱.۳۳%, P = ۰.۴۷۵.)Conclusion: The use of uterine cooling during cesarean section reduced the volume of blood loss and the rate of decline in hemoglobin concentration.

کلیدواژه ها:

Cesarean Section ، Post-Partum Hemorrhage ، Uterus ، delivery