Successful Treatment of Unilateral Klippel-Trenaunay Syndrome With Pulsed-Dye Laser in a ۲-Week Old Infant

Abstract Introduction: Klippel–Trenaunay syndrome (KTS) is a rare congenital mesodermal abnormality characterized by varicose veins, cutaneous capillary malformation, as well as bone and soft tissue hypertrophy.Case Report: A ۲-week-old female infant presented to our clinic because of vascular nevus and progressive enlargement of her right extremities and trunk since birth. The patient was treated with ۵۹۵-nm pulsed-dye laser (PDL). Her port-wine stain (PWS) disappeared completely after third PDL session and the soft tissue hypertrophy stopped. The patient experienced neither recurrence nor any change in size after ۷ years of follow up.Conclusion: PDL can treat KTS completely with no reccurence if it is used in “early stage” of disease. Keywords: Klippel–Trenaunay syndrome Laser Port-wine stain Vascular malformation.